How is a Miscarriage medically managed? How is a Miscarriage medically managed? klinical Some miscarriages may be managed medically using a prostaglandin tablet called Misoprostol to gently open the entrance of the womb allowing the pregnancy to pass. This process can happen at home or in a hospital setting. 0 Likes Post navigation Previous Previous post: What is an Evacuation of Retained Products of Conception (ERPC)?Next Next post: Why did I have a Miscarriage?